City Medical Centre · multi-specialty surgery clinicOpen 24/7

Joint Treatment in Milan Without Surgery

We treat the knee, hip, shoulder and other joints with SVF and PRP. Before anything is decided, your scans are reviewed at no cost

Consultation and review of your scansFree

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Knee joint: regenerative treatment without surgery
Joint treatment without surgery. Free consultation and review of your scans

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What it is

What is regenerative
joint treatment?

Regenerative treatment of the joints relies on material taken from your own body: platelet-rich plasma (PRP) prepared from blood, and the stromal vascular fraction (SVF) obtained from a small sample of adipose tissue. This material is injected into the problem joint to ease pain and inflammation and to support the tissues within it.

  • No surgery — an injection instead of an operation
  • Own tissue — your blood and adipose tissue
  • Ultrasound guidance for every injection
Knee joint: an injection under ultrasound guidance

Who the treatment suits

Your suitability for the treatment is decided by a doctor following an examination and a scan review

Suitable

A doctor reviews knee X-rays with a patient
  • Pain, crunching or stiffness in a joint
  • Painkillers only help for a short time
  • Recovery after injuries and surgery
  • You need a second opinion on your scans
  • You want to avoid or postpone joint replacement
  • Early or moderate arthrosis or arthritis
  • High load on the joints — sport or physical work

Not suitable

A doctor examines a patient's knee
  • Cancer
  • Pregnancy
  • Blood clotting disorders
  • Acute infections, including infection in or near the joint
  • Flare-up of a serious chronic illness
  • Temporary contraindications: fever, flu or a cold, skin inflammation over the joint being treated

Not sure the treatment is right for you?

Leave your number — the coordinator will ask for your scans (X-ray, MRI or ultrasound), and the doctor will tell you whether treatment without surgery suits you.

Find out if it suits me

How it works

How the procedure goes: step by step

Consultation and scan review1

Consultation and scan review

The doctor examines your joint, looks at your X-rays, MRI or ultrasound and decides whether the procedure is right for you. Scans you already have can be sent ahead of the visit.

Blood sample for PRP2

Blood sample for PRP

A small blood draw from a vein provides the material from which platelet-rich plasma with growth factors is later prepared.

Adipose tissue sample3

Adipose tissue sample

About 30 ml of adipose tissue is collected through a puncture on the abdomen or the inner thigh under local anaesthetic. The puncture needs no stitches.

Processing in a centrifuge4

Processing in a centrifuge

After centrifuging, the sample forms separate layers; the stromal vascular fraction is taken from them and combined with the platelet-rich plasma.

Injection into the joint5

Injection into the joint

The doctor injects the prepared material directly into the affected joint, using ultrasound to place it precisely.

Follow-up6

Follow-up

No crutches, no hospital stay — and after the procedure the doctor keeps in touch to follow the joint's response.

Book a consultation

Call or message us — our coordinator will contact you shortly and book your consultation

A doctor talks with a patient about joint treatment
Book a consultation
A doctor talks with a patient about joint treatment

Results

After the procedure

  • Doctor talking warmly with a patient after the procedure

    1 week

    The joint may ache a little more — this is an expected reaction.

  • Doctor consulting an older patient one month after treatment

    1 month

    The pain usually eases.

  • Doctor explaining progress to a patient using a knee joint model

    ~3 months

    Mobility and activity improve.

  • Doctor and patient walking together at a follow-up visit

    ~6 months

    The full effect develops.

How long it lasts differs from person to person and depends on the stage of the condition, body weight, activity and other factors — no one can promise a fixed result.

Comparison

Methods we use

The material comes only from your own blood and adipose tissue, never from donors or synthetics

Cell therapy (SVF) from your own adipose tissue

A little of your adipose tissue is processed to isolate SVF — the stromal vascular fraction, which contains cells involved in repairing tissue. It is then combined with your own plasma and injected into the joint.

A doctor explains SVF cell therapy for the knee to a patient on a tablet

More marked changes in the joint and the wish for a longer-lasting effect are the usual reasons to choose it.

Material
Your adipose tissue and plasma
How it is given
Into the joint, under ultrasound
Duration
The whole procedure is done in one day.

PRP — platelet-rich plasma from your own blood

Plasma rich in platelets and growth factors is separated from a small amount of your blood and injected into the joint. It helps calm inflammation and creates better conditions for tissue repair.

A doctor explains PRP therapy for joints to a patient on a monitor

It may be given alone as a course of injections or combined with SVF.

Material
Your blood from a vein
How it is given
Into the joint, under ultrasound
Duration
The whole procedure is done in one day.

The benefits and timings shown are averaged and given for guidance: the plan and recovery depend on your joint and individual features, and the doctor confirms them at the consultation.

At the consultation the doctor will review your scans and suggest a treatment plan

Free consultation

Book a consultation

Joints

Joints we treat

Treatment covers large and small joints, with the joint, the method and the number of injections chosen after the doctor reviews your scans

  • KneeKneePain on stairs and after walking, meniscus problems, cartilage wear
  • HipHipEarly hip osteoarthritis, groin pain, limited rotation
  • ShoulderShoulderWear of the joint and its tendons, pain when raising the arm
  • ElbowElbowPain caused by overuse or sports strain; worn joint surfaces
  • Hand and wrist jointsHand and wrist jointsPain and stiffness affecting the small finger and wrist joints
  • AnkleAnklePain and stiffness after sprains and old injuries

Advantages

Why patients choose City Medical Centre

We focus on preserving your own joint instead of replacing it, without surgery

Your own tissue

Your own tissue

The material comes only from your own blood and adipose tissue, never from donors or synthetics

No crutches

No crutches

Punctures rather than incisions, local anaesthetic and no lengthy rehabilitation

Second opinion

Second opinion

Your X-rays, MRI or reports get a free independent assessment from a doctor — just send them

Support after the procedure

Support after the procedure

After the procedure we keep in touch and follow the result, not only the day of the injection

About the clinic

A clinic where you can feel at ease

Modern equipment, comfortable rooms and care for every patient

A doctor and a patient at the clinic

Contact us the way that suits you

We will answer your questions and find a convenient time for a consultation

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Price

Joint treatment prices

The cost depends on the joint, the stage of the condition and the method, so the doctor names it after the consultation

FAQ

Joint treatment: frequently asked questions

About the conditions

More about these conditions

Joint treatment in Milan: a short guide

The method relies on your own tissue only, so there is no donor or synthetic material. Plasma is prepared from a small blood sample, and SVF from about 30 ml of adipose tissue taken through a puncture. This is how non-surgical joint treatment works for everyone in Milan.

Most patients from Milan go home the same day and return to normal daily activity within a day or two. During the first week the joint may ache a little more — this is an expected reaction. Pain usually eases over the first month.

Book a free consultation in Milan to find out whether regenerative joint treatment suits you. The doctor names the price after examining the joint and reviewing your scans.

Sources and further reading

  1. NHS — Arthritis
  2. NHS — Osteoarthritis
  3. MedlinePlus — Joint disorders
  4. PubMed / NCBI — Core Recommendations for Osteoarthritis Care: Systematic Review of Clinical Practice Guidelines (2023)
  5. PubMed / NCBI — Managing osteoarthritis (Aust Prescr, 2015)

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