Arthritis Treatment in Milan
For arthritis in the knee, hand, shoulder or another joint, PRP and SVF cell therapy form one part of care — starting with a doctor's review of your tests
No surgery — an injection instead of an operation
Own tissue — your blood and adipose tissue
Ultrasound guidance for every injection
Free consultation
and review of your scans
What is arthritis
and when does this treatment fit?
Put simply, arthritis is joint inflammation. The joint may hurt at rest and at night, feel stiff each morning for more than half an hour, swell, redden and feel warm. Causes include autoimmune diseases such as rheumatoid or psoriatic arthritis, as well as gout, infection or an old injury.
While PRP and SVF can lower inflammation and pain and help the joint's inner tissues, a systemic disease still needs a rheumatologist — these injections do not take their place. They are never given during an active joint infection or a strong flare; the doctor first establishes the type of arthritis and times the procedure.
No surgery — an injection instead of an operation
Ultrasound guidance for every injection
Free consultation and review of your scans
Joints we treat
Any size of joint, large or small: your scans are reviewed first, then the doctor settles on the joint, the method and the number of injections
Elbow
Overuse or sports-strain pain and wearing of the joint surfaces
Hand and wrist joints
Stiffness with pain in the small joints of the fingers and the wrist
Knee
Meniscus issues and cartilage wear, with pain after walking or on stairs
Hip
Early hip osteoarthritis, groin pain, limited rotation
Ankle
Pain and stiffness after sprains and old injuries
Shoulder
Worn joint and nearby tendons, and pain when the arm is raised
Methods we use
Cell therapy (SVF) from your own adipose tissue
From a small sample of adipose tissue we isolate the stromal vascular fraction (SVF), a mix of repair-related cells. Combined with your own plasma, the material is injected into the joint that is affected.
In cases of inflammatory arthritis it comes in once the acute flare has eased, for its effect on local inflammation and repair of tissue.
PRP — platelet-rich plasma from your own blood
Plasma rich in platelets and growth factors is separated from a small amount of your blood and injected into the joint. It helps calm inflammation and creates better conditions for tissue repair.
It may be advised for rheumatoid or other inflammatory arthritis, always as just one part of the overall plan of treatment.
How the procedure goes: step by step
Consultation and scan review
After examining the joint and reviewing your X-rays, MRI or ultrasound, the doctor decides whether the procedure is right for you. Scans you already have can be sent ahead of the visit.
Blood sample for PRP
Platelet-rich plasma with growth factors is prepared later from a small amount of blood taken from your vein.
The doctor tells you in advance which tests are needed.
Adipose tissue sample
About 30 ml of adipose tissue is taken through a puncture on the abdomen or inner thigh, under local anaesthetic; the puncture needs no stitches.
Processing in a centrifuge
A centrifuge spins the sample until it forms layers. The stromal vascular fraction is isolated from them and mixed with platelet-rich plasma.
The whole procedure is done in one day.
Injection into the joint
The affected joint receives the prepared material by direct injection under ultrasound guidance, for precise placement.
Follow-up
The doctor follows how the joint responds and stays in touch after the procedure — and you need no crutches or hospital stay.
Consultation and scan review
After examining the joint and reviewing your X-rays, MRI or ultrasound, the doctor decides whether the procedure is right for you. Scans you already have can be sent ahead of the visit.
Blood sample for PRP
Platelet-rich plasma with growth factors is prepared later from a small amount of blood taken from your vein.
The doctor tells you in advance which tests are needed.
Adipose tissue sample
About 30 ml of adipose tissue is taken through a puncture on the abdomen or inner thigh, under local anaesthetic; the puncture needs no stitches.
Processing in a centrifuge
A centrifuge spins the sample until it forms layers. The stromal vascular fraction is isolated from them and mixed with platelet-rich plasma.
The whole procedure is done in one day.
Injection into the joint
The affected joint receives the prepared material by direct injection under ultrasound guidance, for precise placement.
Follow-up
The doctor follows how the joint responds and stays in touch after the procedure — and you need no crutches or hospital stay.
Follow-up visits
Follow-up visits allow the doctor to track the joint's response and fine-tune the plan: pain generally eases over the first month, mobility improves in about three months, and the full effect develops over roughly six months.
Conditions we treat
Suitability is decided by a doctor following an examination and a review of your scans
What we work with
Arthritis
Arthrosis
Avascular necrosis
Osteoarthritis
Gonarthrosis (knee osteoarthritis)
Coxarthrosis (hip osteoarthritis)
Meniscus pathology and injury
Rehabilitation after injuries and surgery
Inflammatory joint conditions
Contraindications
Cancer
Pregnancy
Blood clotting disorders
Acute infections, including infection in or near the joint
Flare-up of a serious chronic illness
Cancer
Pregnancy and breastfeeding
Serious heart, kidney or liver disease
Temporary contraindications: fever, flu or a cold, or inflamed skin over the joint being treated
Book a consultation
Call or message us —
our coordinator will contact you shortly
and book your consultation
Book a consultation
Call or message us —
our coordinator will contact you shortly
and book your consultation
After the procedure
After the procedure most patients leave the same day and resume ordinary daily activity within a day or two, with small dressings on the puncture sites. Slightly more aching in the joint during the first week is an expected reaction. Pain generally eases in the first month, mobility and activity get better over about three months, and the full effect develops over roughly six months. Duration varies from one person to another depending on the stage of the condition, body weight, activity and other factors — nobody can promise a set outcome. If a rheumatologist is treating you, talk to them before you stop any prescribed medication.
Why patients choose City Medical Centre
We aim to preserve your own joint instead of replacing it — treatment without surgery
Your own tissue
Everything used comes from you — your blood and adipose tissue — with no synthetic or donor material
No crutches
Local anaesthetic, punctures rather than incisions, and no long rehabilitation
Second opinion
Free of charge, a doctor gives an independent assessment of the X-rays, MRI or reports you send
Support after the procedure
After the procedure we keep in touch and follow the result, not only the day of the injection
Arthritis treatment prices
You learn the cost from the doctor after the consultation, as it depends on the joint, the method and the type of arthritis
Service
Price
Book a consultation
Call or message us —
our coordinator will contact you shortly
and book your consultation
Book a consultation
Call or message us —
our coordinator will contact you shortly
and book your consultation
Joint treatment: frequently asked questions
What is arthritis and what are its symptoms?
In arthritis the joints are inflamed. People usually notice pain at night and at rest, stiffness in the morning that lasts more than 30 minutes, swelling, and redness and heat over the joint. It can be caused by autoimmune conditions such as rheumatoid arthritis, by infections, by gout or by psoriasis.
Can PRP help with rheumatoid arthritis?
PRP may help with local inflammation, pain and swelling in rheumatoid and other inflammatory arthritis. The platelets release growth factors that affect tissue repair and the immune response. Your rheumatologist's treatment stays in place — PRP complements it and does not replace it.
Can psoriatic arthritis be cured?
Psoriatic arthritis is a chronic disease that currently cannot be cured completely. The goal is a long remission — keeping inflammation under control and preventing joint deformity — and regenerative injections can be one part of that plan.
How does SVF work in autoimmune arthritis?
SVF includes cells that can modulate the immune response at the site and support the repair of damaged joint tissue. Since research in this field is still ongoing, the doctor will discuss realistic expectations for your form of arthritis.
When is the treatment not suitable?
If you have an active joint infection, a severe flare, cancer or a blood clotting disorder, or are pregnant, the procedure is not done; the doctor postpones it or offers another option.
How is knee arthritis different from osteoarthritis?
An autoimmune reaction, infection or gout can inflame the knee — that is knee arthritis, with redness, warmth, marked swelling and tenderness to touch. Osteoarthritis is cartilage wear, usually noticed as a dry crunch and aching pain when the knee moves.
Why does an arthritic joint hurt even at rest?
PRP, SVF and other treatment aimed at reducing inflammation can ease this pain, because inflammation keeps stimulating the joint's pain receptors all the time — at rest, on movement and at night.
Can joint injections be done during pregnancy?
No. Because pregnancy is a contraindication to joint injections, including PRP and SVF, arthritis treatment during pregnancy is only decided jointly by a rheumatologist and an obstetrician.
Can I get a second opinion on my tests and scans?
Yes — a doctor will look through your X-rays, MRI, ultrasound or blood test results free of charge and tell you whether regenerative treatment could fit your type of arthritis.
What happens if rheumatoid arthritis is not treated?
If it is not treated, it may cause permanent deformity of the joint, loss of function, osteoporosis and damage to internal organs — the heart, lungs and kidneys among them. Treating it in time helps prevent these complications.
City Medical Centre licences
Other services at our clinic
Arthritis treatment in Milan: a short guide
Regenerative injections are not done during an active joint infection or a severe flare. In Milan, the doctor chooses the right moment, usually once the acute inflammation has settled.
Pain usually eases over the first month, and mobility improves over about three months. For patients from Milan, the full effect develops over around six months, and its duration differs from person to person.
Book a free consultation in Milan to find out whether PRP or SVF could help your arthritis. The doctor names the price after examining the joint.
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