SVF and PRP Joint Therapy in Istanbul
Cell therapy (SVF) and platelet-rich plasma for knee, hip and shoulder joints and beyond, plus a free look at your scans first
No surgery — an injection instead of an operation
Own tissue — your blood and adipose tissue
Ultrasound guidance for every injection
Free consultation
and review of your scans
What is regenerative
joint treatment?
Material from your own body is at the heart of regenerative joint treatment — PRP, a platelet-rich plasma derived from blood, and SVF, the stromal vascular fraction derived from a small sample of adipose tissue. Placed into the affected joint by injection, it reduces pain and inflammation and supports the joint's tissues.
This treatment suits people with painful joints who would like to avoid or delay surgery, or who have been told that only a joint replacement will help. The earlier the stage, the better the prospect of a lasting result — the doctor judges this from your scans.
No surgery — an injection instead of an operation
Ultrasound guidance for every injection
Free consultation and review of your scans
Joints we treat
Large and small joints — the doctor chooses the joint, the method and the number of injections after reviewing your scans
Elbow
Pain after overuse or sports strain, wear of the joint surfaces
Hand and wrist joints
Stiffness and aching in the finger and wrist joints
Knee
Cartilage wear, meniscus problems, pain on stairs and after walking
Hip
Early hip osteoarthritis, groin pain, limited rotation
Ankle
Pain and stiffness after sprains and old injuries
Shoulder
Arm-raising pain, with wear of the joint and the tendons around it
Methods we use
Cell therapy (SVF) from your own adipose tissue
From a small sample of your adipose tissue, the stromal vascular fraction (SVF) is isolated — cells that are involved in tissue repair. This fraction, combined with your plasma, is injected into the affected joint.
It is typically chosen for more pronounced joint changes, with a longer-lasting result in mind.
PRP — platelet-rich plasma from your own blood
The joint receives an injection of plasma rich in platelets and growth factors, separated from a small amount of your blood. It helps soothe inflammation and creates better conditions for the tissues to repair.
Used by itself as an injection course, or together with SVF.
How the procedure goes: step by step
Consultation and scan review
An examination of the joint and a review of your X-ray, MRI or ultrasound results let the doctor decide whether the procedure suits you. Please send any scans you have before the visit.
Blood sample for PRP
The nurse takes a small amount of venous blood; platelet-rich plasma with growth factors is prepared from it afterwards.
The doctor tells you in advance which tests are needed.
Adipose tissue sample
A small portion of adipose tissue (about 30 ml) is taken under local anaesthetic through a puncture on the abdomen or inner thigh. There is no need for stitches.
Processing in a centrifuge
In a centrifuge the sample separates into layers. The stromal vascular fraction is then isolated and combined with the platelet-rich plasma.
The whole procedure is done in one day.
Injection into the joint
The doctor injects the prepared material directly into the affected joint, using ultrasound to place it precisely.
Follow-up
There are no crutches and you do not stay in hospital. After the procedure the doctor stays in contact and tracks the joint's response.
Consultation and scan review
An examination of the joint and a review of your X-ray, MRI or ultrasound results let the doctor decide whether the procedure suits you. Please send any scans you have before the visit.
Blood sample for PRP
The nurse takes a small amount of venous blood; platelet-rich plasma with growth factors is prepared from it afterwards.
The doctor tells you in advance which tests are needed.
Adipose tissue sample
A small portion of adipose tissue (about 30 ml) is taken under local anaesthetic through a puncture on the abdomen or inner thigh. There is no need for stitches.
Processing in a centrifuge
In a centrifuge the sample separates into layers. The stromal vascular fraction is then isolated and combined with the platelet-rich plasma.
The whole procedure is done in one day.
Injection into the joint
The doctor injects the prepared material directly into the affected joint, using ultrasound to place it precisely.
Follow-up
There are no crutches and you do not stay in hospital. After the procedure the doctor stays in contact and tracks the joint's response.
Follow-up visits
Through follow-up visits the doctor monitors the joint and adjusts the plan. As a rule, pain eases over the first month, mobility improves over around three months, and the full effect appears over about six months.
Conditions we treat
A doctor decides whether the treatment suits you after examining you and reviewing your scans
What we work with
Arthritis
Arthrosis
Avascular necrosis
Osteoarthritis
Gonarthrosis (knee osteoarthritis)
Coxarthrosis (hip osteoarthritis)
Meniscus pathology and injury
Rehabilitation after injuries and surgery
Inflammatory joint conditions
Contraindications
Cancer
Pregnancy
Blood clotting disorders
Acute infections, including infection in or near the joint
Flare-up of a serious chronic illness
Cancer
Pregnancy and breastfeeding
Serious heart, kidney or liver disease
Temporary contraindications: fever, a cold or flu, skin inflammation over the joint to be treated
Book a consultation
Call or message us —
our coordinator will contact you shortly
and book your consultation
Book a consultation
Call or message us —
our coordinator will contact you shortly
and book your consultation
After the procedure
The majority of people are discharged the same day and resume normal daily activity within a day or two; the puncture sites are simply covered with small dressings. Expect the joint to ache somewhat more in the first week — that reaction is normal. Pain usually eases in the first month, mobility and activity improve over roughly three months, and the full effect develops over around six months. The duration varies from person to person and depends on the stage of the condition, body weight, activity and other factors; no one can promise a fixed result. Individual advice on exercise and load for the first weeks comes from your doctor.
Why patients choose City Medical Centre
We focus on preserving your own joint instead of replacing it, without surgery
Your own tissue
We rely solely on your own blood and adipose tissue, without donor or synthetic material
No crutches
Punctures rather than incisions, local anaesthetic and no lengthy rehabilitation
Second opinion
A doctor gives a free, independent assessment of the X-rays, MRI or reports you send us
Support after the procedure
We follow the result after the procedure and stay in contact, not only on the day of the injection
Joint treatment prices
How much it costs depends on the joint, the method and the stage of the condition — the doctor tells you after the consultation
Service
Price
Book a consultation
Call or message us —
our coordinator will contact you shortly
and book your consultation
Book a consultation
Call or message us —
our coordinator will contact you shortly
and book your consultation
Joint treatment: frequently asked questions
What is the difference between PRP and SVF?
SVF is a cell fraction isolated from a small sample of your adipose tissue, whereas PRP is platelet-rich plasma prepared from your blood. They work differently and are frequently combined for a stronger regenerative effect in the joint.
Is the treatment safe?
Your own tissue is used in both methods, which keeps the risk of rejection or an allergic reaction very low. Any injection may cause temporary pain, swelling or bruising; infection is rare. The doctor explains your individual risks at the consultation.
How long does the effect last?
That varies. Often the effect after PRP lasts several months up to about a year, and after SVF it can be longer. The duration depends on the stage of the condition and on your body, so a fixed result cannot be promised.
Who should not have the procedure?
The doctor checks at the consultation that you have no cancer, acute infection or blood clotting disorder, are not pregnant and are not in a flare-up of a serious chronic illness — in these cases the procedure is not done.
Does hip osteoarthritis (coxarthrosis) always need surgery, or can it be treated without?
PRP or SVF injections combined with exercise therapy and physiotherapy can, at early stages, reduce pain and improve movement. For a joint that is already badly damaged, replacement may be the more realistic option — after seeing your scans, the doctor will tell you honestly.
Can avascular necrosis of the hip be treated?
At stages 1–2, SVF therapy can be considered to help the blood supply to the femoral head and delay joint replacement; at later stages surgery is usually necessary.
Why try to avoid joint replacement?
Replacement is major surgery that brings long rehabilitation, risks including infection, and implants that may eventually need redoing. So with early or moderate changes it often makes sense to first try preserving your own joint.
Can I get a second opinion on my scans?
Yes. A doctor will review your X-rays, MRI, CT or medical reports free of charge once you send them, and explain whether the procedure could suit you and what else might be needed.
How soon can I return to normal life?
Most people return within a day or two. There is no long rehabilitation and no need for crutches; the doctor gives advice on load and exercise for the first weeks.
Does the treatment help with shoulder pain?
For the rotator cuff and the shoulder joint, PRP is used; SVF may be considered in more advanced shoulder arthritis. Whether this is right for you depends on the cause of the pain, which the doctor determines first.
City Medical Centre licences
Other services at our clinic
Joint treatment in Istanbul: methods, steps and price
SVF and PRP work in different ways. PRP helps calm inflammation and creates better conditions for repair; SVF contains cells involved in tissue repair and is chosen when changes are more pronounced. For patients from Istanbul, the doctor often combines the two.
Most patients from Istanbul go home the same day and return to normal daily activity within a day or two. During the first week the joint may ache a little more — this is an expected reaction. Pain usually eases over the first month.
A consultation is the first step for every patient from Istanbul. It is free, and after it you know the method, the number of injections and the cost.
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